Zoloft is a selective serotonin reuptake inhibitor


Drug Description
Zoloft is a selective serotonin reuptake inhibitor. The medicine is distributed as oral tablets (25mg, 50mg and 100mg) that are dispensed in bottles. An oral concentrate is also available.

Drug Uses
The key compound is sertraline hydrochloride which has proved to be an effective treatment for major depressive disorders, as well as Obsessive Compulsive Disorder, PTSD (Post Traumatic Stress Disorder), PMDD (Pre-menstrual Dysphoric Disorder, and Social Anxiety Disorder. Sertraline acts as a chemical stabilizer in the brain to reduce the distressing symptoms associated with these conditions.

Dosage Instructions (Adults)
For Obsessive Compulsive Disorder and Major Depressive Disorder the usual dose is 50mg a day.

For Social Anxiety Disorder, Post Traumatic Stress Disorder and Panic Disorder the usual dose is 25mg a day for a week. After this period the dose is increased to 50mg a day.

For Pre-menstrual Dysphoric Disorder the usual dose is 50mg a day during the menstrual cycle.

Zoloft may be administered with or without food. Drink water or liquid when taking the tablets.

The oral concentrate should be diluted with water, lemonade, ginger ale, orange juice, or lime/lemon soda. Do not use any other liquids other than these. Follow the dosing procedure as explained on the instruction pamphlet.

Always adhere to a physician’s instructions regarding dosage. Some patients may require adjusted doses which will be determined by a physician.

Essential information and/or warnings
Zoloft may induce suicidal actions or thoughts. If you have a family history of depressive disorders or suicidal deeds or thoughts, inform the physician. Feelings of suicide are usually evident in the early stages of treatment.

Report the following symptoms to a physician: agitation, anxiety, insomnia, panic attacks, hostility, irritability, aggressiveness, impulsiveness, mania, depression, or restlessness. The dose may need adjusting.

Because Zoloft might not react well with other medicines, the physician will need to know details of all supplements, remedies and medications that the patient is using.

Inform your physician if you suffer with epilepsy, kidney or liver disease, Bipolar Disorder, or if you have contemplated suicide, or if you have abused any drugs.

Zoloft may affect the ability to concentrate. Do not drive or undertake any activity that requires mental alertness until you are sure that this medicine does not impair concentration.

Can pregnant and breastfeeding mothers use this drug?
Zoloft may cause serious respiratory problems in an unborn or newborn baby. Pregnant women should not use Zoloft. However, if you become pregnant while using this medicine, speak to your physician urgently but do not stop treatment until he or she tells you to. Although it has not yet been medically proved, Zoloft could harm breast milk. Discuss the risk with a physician.

Potential Side Effects
SIDE EFFECTS THAT WILL REQUIRE MEDICAL TREATMENT: Allergic reaction (indicated by swelling, rash, difficulty breathing), high fever, rigid muscles, irregular heart rate, heavy sweating, tremors, severe diarrhea or vomiting, lack of co-ordination, lack of appetite, hallucinations, breathing problems, convulsions, confusion, memory problems, weakness, concentration problems, or severe headache.

COMMON SIDE EFFECTS: fatigue, dizziness, drowsiness, dry mouth, constipation, mild nausea or diarrhea, change in weight, insomnia, or sexual problems. These should disappear after a few days. If not, speak to your physician.